Application of Glove Box in Medical Industry

As we all know, vacuum glove box products are widely used in ultra-pure environments without H2O, oxygen, and dust. They are essential laboratory equipment in physical and chemical research. In recent years, vacuum glove boxes have also been widely used in the development and production of lithium batteries. Glove boxes are playing a key role in more and more industries.

Today we introduce the application case of vacuum glove box in the medical industry

Mask Bacterial Filtration Efficiency (BFE) Tester

It adopts a design system based on negative pressure biosafety working environment, which is safe and convenient to use and controllable in quality. The method of simultaneous comparison and sampling of dual gas paths improves the accuracy of sampling and the detection efficiency is high. Applicable to inspection and quarantine units, metrological inspection departments, scientific research institutes, mask production and other related departments for the performance test of the bacterial filtration efficiency of masks.

Standards compliant

"Technical Requirements for Medical Surgical Masks" YY0469-2004

American Society for Testing Materials ASTMF2100, ASTMF2101

European EN14683 standard

Technical characteristics

 Professional negative pressure experiment system to ensure the safety of operators and the environment

 High negative pressure working chamber, two-stage high efficiency filter, 100% safe discharge

 Using two channels of six-level Anderson accurate sampling

 Built-in peristaltic pump, the flow rate of the peristaltic pump is adjustable

 Special microbial aerosol generator, the flow rate of the bacterial liquid spray can be set, and the atomization effect is good

 Industrial-grade microcomputer control, color touch screen, easier operation

 USB interface, support U disk data transfer

 Built-in LED lighting in the vacuum box for easy observation

 Built-in ultraviolet disinfection lamp to enhance protection effect

 Front openable sealed glass door, convenient for observation and operation

 Detachable bracket with adjustable height                                                                                        

 Supporting and moving dual purpose casters

 Seamless connection with laboratory information management system

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What Needs to be Prepared before Glove Box Operation

The glove box equipment commonly used in the laboratory mainly consists of a tank, a gas purification system, a transition chamber, a vacuum pump, a control system and additional functions. The glove box equipment is a completely sealed vacuum laboratory instrument.

    When we operate the vacuum glove box, the gas is purified from the filtering and purification system of the fuel tank and sent back to the fuel tank equipment to repeat the cycle. The primary diluent is to separate radioactive substances or other toxic substances. The glove box is equipped with a viewing window to facilitate experimental operations. .

 Therefore, we also have some general precautions when operating the glove box. If you should consult special medicines or unconventional supplies before the operation, users should not leave long nails, nor can they carry jewelry, rings or other things that may damage the gloves. It is necessary for the operator to wear gloves in the glove table of the glove box. Before use, check the working pressure plan on the glove box panel and the adjustment should be within ±4 mbar.

    Operate in the glove box, be careful and tidy, and be careful when using tweezers and other sharp objects to prevent piercing the gloves; cover the electrolyte immediately after using it; put the items back in place when they are used up; wipe the battery after pressing the battery Clean the electrolyte on the tablet press; put the waste into the waste bin; after the operation, check that the above items are correct before leaving the cabin.

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Two Core Advantages of Etelux Cycle Purification Glove Box


1. The extremely low system leakage rate of the circulating glove box:

The company’s glove box leakage rate is <0.005 VOL%/H, tested by a national authoritative testing organization: the measured value of the standard glove box leakage rate is <0.001 VOL%/H (the glove box is under ±800Pa pressure) , Far lower than the internationally accepted standard of <0.05VOL%/H, the system adopts the oxygen method and has the function of automatically detecting the leakage rate.


After the assembly is completed, the complete glove box system adopts three sets of inspection procedures:


1. Detection of positive and negative pressure changes;


2. Helium mass spectrometer leak detector for air tightness testing;


3. Leak rate detection by oxygen method.


2. The circulating glove box has a strong deoxygenation and H2O removal cycle purification capacity:


The circulatory purification system of Etelux glove box adopts the original purification material reduction and regeneration patented technology. This patented technology can use a steel cylinder of reducing gas to reduce and regenerate 8-10 kg of deoxidizer, so our company’s deoxidizer fill volume It can reach 8 kilograms, and the filling amount of H2O-removing agent matching with the deoxidizing agent can also reach 16 kilograms. The core patented technology of our company's purification material reduction and regeneration has the following advantages:


The glove box greatly improves the reduction and regeneration rate of the purification material, and the reduction and regeneration rate of the deoxidizer is >80%


A cylinder of reducing regeneration gas in the glove box can regenerate 8-10 kilograms of deoxidizer (the amount of deoxidizer filled is determined by the amount of deoxidizer that can be regenerated by a cylinder of regenerating gas. If a cylinder of reducing regeneration gas can only reduce and regenerate 4 kg of deoxidizer, the more filled deoxidizer is also invalid, so the amount of deoxidizer in the same industry is only about 5 kg), which matches the filling amount of the dewatering agent is 16 kg (the filling amount of the dewatering agent is determined according to the effective filling amount of the deoxidizing agent, and the filling ratio of the dewatering agent and the deoxidizing agent of our company is 2:1) . So the amount of oxygen and H2O removal is greater


The reduction and regeneration interval of the glove box purification material is longer, and the interval period can reach more than 12 months under normal use (the interval period is determined by the following four aspects under normal use conditions: a. The leakage rate of the glove box; b. The amount of oxygen and H2O removed by the purification material; c. The characteristics of the material during the user's use; d. The user's usage habits, etc.), it is precisely because of the ultra-low leakage rate and powerful oxygen and H2O removal of our company's glove box products , So the regeneration interval of the purification material is longer.


The glove box greatly saves the cost of using the glove box (saving reduction gas), time cost and maintenance cost


The glove box greatly prolongs the service life of the purification material. Under normal use, the deoxidizer and dewatering agent in the glove box of our company do not need to be replaced (under normal use, the deoxidizer can be restored and regenerated more than 20 times. , Our company's purification material reduction regeneration interval can be up to one year or more than 12 months, so our company's purification material replacement cycle is more than 15 years, and the service life of the glove box is about 15 years, which means that in normal use In the state, the glove box does not need to replace the deoxidizer and dewatering agent)


  a. Filling amount of dewatering agent: 16KG, effective dewatering capacity: 5KG, no need to replace


  b. Filling amount of deoxidizer: 8KG, effective deoxidizing capacity: 120L, no need to replace


  c. The filling amount of activated carbon: 6KG, generally replaced once every two years (according to the actual application of the glove box)

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The Scope and Structure of the Vacuum Glove Box

 In many chemical reactions and pre-processing of test samples, some substances are very sensitive to oxygen and H2O and cannot be carried out under normal circumstances. Although the chemical reaction of this type of substance can be carried out in a vacuum container, it cannot be operated, which makes the pretreatment of the chemical reaction sample of this type of substance very difficult.

     The use of a vacuum glove box allows these substances to operate, react and test freely in the absence of oxygen and H2O. Therefore, it is used in chemistry, chemical industry, and biology, especially in certain catalysts and metal organics (such as M0 sources, etc.) ) Has a wide range of applications in preparation and research.

     The glove box is a kind of equipment that supplies an anhydrous and oxygen-free environment. The equipment is mainly composed of a display system, a transition chamber, a vacuum system, a control system, a chamber, a recycling purification and regeneration system, etc. It can also be combined with a gas purification system, integrated operation of solvent filtration system and H2O and oxygen display system. The box body is made of high-quality steel plate or mirror stainless steel argon arc welding, and double-layer tempered glass. Beautiful and novel, stable function.

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The Effect of Gap Size on Vacuum Pump Unit

    During the use of the vacuum pump unit, the size of the gap will have a relatively obvious impact on the function of the product. When it is severe, the equipment will not work normally. What are the reasons for this problem and what specific impact will it cause?


    1. For axial single-effect pumps, the axial gap refers to the end gap between the impeller and the pump body. It can be seen that when the gap exceeds a certain value, the relative pumping time required by the pump with the same axial gap is related to the required vacuum degree. For the same vacuum degree, the relative pumping time varies with the addition of the axial gap.


    2. The gap of the vacuum pump unit is the effect of volume loss or volume power on the pump function. Take the single-effect water ring vacuum pump as an example to illustrate the regularity of this effect. The gap of the water ring vacuum pump is divided into radial gap and axial gap.


    After the vacuum pump unit is installed, it is recommended to carefully check whether the gap running-in of each part meets the requirements, to avoid excessive gaps that may cause the unit to function abnormally, and even cause greater damage to the unit.

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Test Run, Start-Up and Shutdown Operations Of Vacuum Negative Pressure Station

In order to ensure that the various operations of the vacuum negative pressure station are in standard conditions, so as to ensure the correct operation of the operators and ensure the safe production, the commissioning, startup and shutdown operations of the equipment must be standardized. The correct operation methods are as follows.


     1. Connect the power line and grounding line, and check whether the main voltage is correct and the three-phase power supply is correct.


     2. Check whether the H2O level is in the proper position. There is a mark on the H2O level gauge of the existing vacuum pump station.


     3. Whether all valves are open.


     4. Check whether all electric control lines of the vacuum negative pressure station are connected.


     5. Check whether the water ring pump is stuck by hand before starting.


     6. Within 2 seconds after pressing the start button, immediately press the stop button to check whether the direction of rotation is consistent with the direction of the arrow on the end face (shaft extension) of the nose. If the direction of rotation is wrong, please exchange any two of the three power cords.

View more quality glove boxes with low price and free shipping all over the world. 

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Nine Glove Box Expansion Configuration Components of the Glove Box

Glove box ultra-low temperature water tank, glove box independent purification unit,

Glove box high-power conductor, glove box spin coater,

KF40 insulated guide post for glove box, lift-up movable window for glove box,

Glove box evaporation machine, glove box laser injection quartz window, glove box T-shaped transition chamber

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Nine Components of Isolation Glove Box

1. Chamber (isolate the body of of the glove box)


2. Antechamber door or transition compartment (isolate the port of the glove box)


3. Cabinet lighting (isolate the nerves of the glove box)


4. Window (isolate the eyes of the glove box)


5. Glove operation port (isolate the arm of the glove box)


6. Move the bottom frame (isolate the thigh of the glove box)


7. Power socket in the box (isolate the brain of the glove box)


8. Box filter, box breathing valve (isolation of the breathing system of the glove box)


9. Negative pressure fan (mostly used for gas isolation) (isolate the lungs of the glove box)

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Which Points Should be Paid Special Attention to When Using the Glove Box?

1) After operating the glove box, fill in the operation record in time, including "the user, the water and oxygen value, and what operation to do".

2) When replacing the gas cylinder in the glove box, the pressure is set to the default value ±4mbar.

3) The daily work pressure is set according to the operating comfort. When not in use for a long time, the pressure is set to 1-6mbar.

4) Regularly check the wear of gloves, check the vacuum pump oil level (between the upper and lower marks), and increase the pump oil appropriately.

5) Clean the water probe once every 2 to 3 months to ensure accurate detection. (Also refer to the actual situation of the environment in different user boxes)

6) If you often use organic solvents in your glove box, it is recommended that you replace the organic solvent adsorption materials regularly, not more than one year at the latest.

7) Replace the filter element regularly, no more than two years at the latest.

8) Decide to replace the vacuum pump oil cycle according to the actual situation of your glove box. For example, the pump oil turns black or yellow, there is water in the pump oil or there are more organic solvents. The oil replacement cycle should not exceed 2 years at the latest.

9) If a lot of organic solvents are inevitably exposed during the experiment, the cycle needs to be stopped to do the experiment. After the experiment is completed, clean it first, and then start the cycle.

10) When the environment in the box is poisonous or harmful, the exhaust port of the vacuum pump, the exhaust port of the air blower and the exhaust port of the cleaning valve must be exhausted to the outdoors with an exhaust pipe (exhaust gas treatment is required if it is not allowed to be exhausted outdoors).

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What is the Function of the Glove Box?


1. Closed circulation: The vacuum glove box and the gas purification system form a closed circulation system, and the gas purification system provides gas circulation power.


2. Man-machine dialogue: equipped with color touch screen, English interface, realize man-machine dialogue, convenient operation


3. Automatic control (the system is controlled by the integration of the color touch screen man-machine interface and the PLC program control system)


Realization function: manual/automatic control chamber pressure;


Manual/automatic control of the purification status of the gas purification system;


Automatically control the reduction process of the gas purification system;


Manual/automatic purification system reduction, purification and conversion purification column (when equipped with dual purification columns);


Automatic chamber atmosphere alarm;


Setting of atmosphere and pressure parameters in the box and manual/automatic conversion;


Parameter setting of automatic control function of gas purification system;


Check system history;


Working condition detection of the actuator of the gas purification system;


The operation error and warning prompt of the program control system.

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